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Mold has recently become a hot-button issue, with horror stories appearing on the news of unsuspecting people suffering from devastating illnesses caused by harmful fungi. Lawsuits against landlords and builders are increasing as more people seek legal help for compensation for mold-related sickness. It begs the question, “Why now?”

Since ancient times, humans have lived with mold, with texts like the Bible referencing the toxic substance. If mold has existed for thousands of years, why is there so much interest in it now? Has it become more toxic than 10, 20, or 50 years ago? What’s changed?

The Impact of Scientific Research on Understanding Mold

While some scientists have theorized that mold is now more toxic than it was in the past, the most likely answer is that improved detection techniques make it easier to find hidden mold. The days of searching for mold spores in air samples are behind us. We now know inhalation isn’t the only way this fungus can cause sickness. Although it’s highly prevalent, some strains are more harmful than others, and we now have the tools to identify and address mold and mycotoxin exposure.

Mold Detection and Symptom Identification

It’s now possible to detect elevated mold counts and toxic species in a variety of areas, including:

  • Household dust
  • Furniture
  • Carpet
  • Heating and cooling systems
  • Ductwork
  • Air purifiers
  • Mattresses
  • C-PAP machines
  • Car ventilation systems

Mold spores were likely present in these locations before but were untreated due to a lack of understanding of the signs of mycotoxin poisoning. Research into the topic unveiled unexpected symptoms previously unknown to scientists. For example, toxic black mold under the kitchen sink can cause dizziness while cleaning the dishes. Sufferers would seek medical help only to receive a diagnosis of a vague ailment like hypersensitivity pneumonitis, a lung inflammation, or vertigo. For many, the symptoms would continue as they underwent unsuccessful treatments that failed to target the real culprit.

Exciting Advancements in Mold Detection

Advanced DNA extraction techniques like MSqPCR (Mold-Specific quantitative PCR) have improved mold awareness and solved many mysterious illnesses. While we already knew that mold and mold toxins caused sickness, including liver and kidney damage, cancers, and even death, inspectors lacked the necessary lab tests to identify the fungus in indoor spaces through corresponding lab tests. Now, however, healthcare workers can test a patient’s blood for mold exposure markers, opening doors to effective treatments that were once closed. Armed with these new testing techniques, our knowledge of mold and its effects has skyrocketed.

More than a decade after implementing this new technology, we can better understand and link occupants’ symptoms with mold contamination in buildings and even identify which mold species cause the strongest reactions.

The History of Mold Detection

In 2004, the Institute of Medicine released a report titled ” Damp Indoor Spaces and Health,” which would pave the way for modern-day advancements in mold detection. It outlined the results of a study showing the connection between damp indoor spaces and mold to illness. The report recommended developing better measurement methods for specific microorganisms using DNA-based and other advanced technologies.

As a result of this report, the US Environmental Protection Agency (EPA) developed a DNA-based test called the ERMI (Environmental Relative Mold Index) that provides a straightforward, objective, sensitive, and standardized method of assessing mold markers in indoor spaces. The test uses dust samples collected from homes and provides highly accurate results. It is important to note that the EPA considers the ERMI a research tool and doesn’t recommend it as the sole testing technique for residential or commercial spaces.

As time progressed, air-quality professionals began using a similar DNA-based testing technique to identify mold in buildings. These techniques drastically improved the ability to discover mold in areas where previous air sample tests could not. These discoveries led to a more comprehensive understanding of what happens when mold is disturbed. It also answered the questions of why people were becoming sick during mold remediation and whether a person transports mold when moving from one contaminated space to one without mold (the mold spores attach to their belongings, contaminating the new space.)

In 2009, the World Health Organization (WHO) concluded that dampness and mold in interior spaces led to a 30% to 50% increase in respiratory and asthma-related sickness. They also found a correlation with higher ERMI values in homes and a greater likelihood of asthma among occupants. Understanding proper cleaning techniques and the best way to remove mold fragments, mycotoxins, and other mold by-products greatly impacted how professionals treated mold infestations.


Recognizing water damage, moisture, and visible mold remain important aspects of mold inspections, but new technologies allow us to see once-invisible spores. We now understand why some people exhibit symptoms even when mold isn’t easily identified. As in law enforcement, DNA technology is an increasingly powerful forensic tool changing the game for mold inspectors and healthcare workers alike.